What is Sermorelin Therapy?
Sermorelin is a bioidentical hormone injection that is genetically engineered to stimulate the secretion of growth hormone releasing hormone (GHRH) from the hypothalamus — a gland adjacent to the pituitary gland. Sermorelin is a peptide that contains 29 amino acids that aid in the production of HGH in the body. As we age, human growth hormones (HGH) naturally diminish—Sermorelin fuels the pituitary gland’s ability to release HGH naturally.
Our body’s human growth hormone output peaks in our mid-20s, and by the time we are in our 40s, those HGH levels diminish by as much as 40%. Sermorelin injections are one of the safest and most effective ways to treat children and adults suffering from growth hormone deficiency.
Growth hormone deficiency (GHD) is a condition characterized by the inadequate secretion of growth hormone from the anterior pituitary gland. GHD can be present from birth, resulting from genetic mutations or from structural defects in the brain. It can also be acquired later in life as a result of trauma, infection, radiation therapy or tumor growth within the brain.
Growth hormone deficiency is characterized by a number of variable symptoms. When these symptoms are severe, they can reduce people’s ability to function socially and professionally, which can dramatically reduce quality of life. Natural HGH levels typically begin to diminish after age 30, causing both men and women to start feeling older, weaker and uncomfortable.
Symptoms of GHD include:
- In increase in body fat
- Impaired concentration and memory
- Increased body fat, especially around the waist
- Sleep disturbances/insomnia
- Anxiety and depression
- High LDL “bad” cholesterol & high triglycerides
- Decreased sexual function and interest
- Greater sensitivity to heat and cold
- Decreased muscle mass (lean body mass)
- Less strength, stamina and ability to exercise without taking a rest
- Loss of bone density
Sermorelin Therapy consists of daily injections of sermorelin acetate, a bio-identical hormone that stimulates the pituitary gland to produce increased levels of human growth hormone. This natural stimulation of the pituitary gland sustains and elevates the production of growth hormone mechanisms that decline with age.
To determine the best treatment method, the physician will start by analyzing the results of each patient’s medical history, physical exam and blood test results. Sermorelin injections are initially prescribed for everyday use, though their frequency is decreased over time per your doctor’s instructions. Once optimal levels are sustained, injection frequencies can be decreased or stopped altogether.
What are the Benefits of Sermorelin Therapy?
Sermorelin Therapy can help you look younger because it improves skin elasticity by allowing it to hold more water, as it did in your youth. The most outwardly visible benefits of Sermorelin treatments include tighter, softer and plumper skin. With Sermorelin injections, patients typically notice a decrease in wrinkles, a reduction in skin sagging and firming of the skin.
Benefits of Sermorelin Therapy include:
- Higher energy levels
- Reduction of abdominal fat
- Decreased wrinkles
- 15% average decrease in fat;
- 8% average increase in muscle/lean body structure
- Swifter healing of injuries, fractures and wounds
- Improved immune system/more resistance to infection
- Improvement in overall physical and mental well-being
- Improved exercise tolerance
- Improved mineral balance
- Improved heart and kidney function.
- Improved Skin Texture & Elasticity
- Better Sleep and Reduced Sleep Disturbance
- Healthier Cardiovascular & Immune System
- Improved Bone Density & Strength
- Loss of Body Fat & Helping Prevent Weight Gain
- Increased Muscle Mass and Ability Rebuild Lost Muscle
- Increase in Sex Drive, Sexual Potency & Frequency
- Improved Mental Function, Focus & Concentration
What are the Advantages of Sermorelin Therapy?
Sermorelin acetate is a biological active analog of growth hormone releasing factor (GRF 1-44) which is a growth hormone releasing hormone (GHRH) that is naturally produced by the human brain to stimulate production and secretion of human growth hormone (HGH) by the pituitary gland. Sermorelin is not a growth hormone; it is a growth hormone secretagogue, which means that it stimulates the pituitary gland by binding to specific receptors to increase the production and secretion of HGH. As a youth, ample amounts of growth hormone releasing hormone (GHRH) are produced so that the pituitary gland is able to provide the body with sufficient growth hormone to sustain health, vitality and otherwise normal aspects of human form and function. While aging, GHRH declines causing reduced production and secretion of pituitary HGH and thereby increasing growth hormone insufficiencies that erode health, stamina and vitality during later life.
This therapy consists of daily injections of Sermorelin acetate which stimulates the pituitary gland to produce increased natural secretion of human growth hormone. Since Sermorelin acetate is approved as safe for use in children to increase their production of growth hormone, it is considered safe for use in increasing the natural production of growth hormone in adults deficient in growth hormone. Each person’s individual needs are used to determine dosing. The result is a safer and more natural increase of the hormone, and as a result there are very few if any side effects. Sermorelin acetate can be a very effective anti-aging supplement, and many people have experienced excellent results with the therapy.
Sermorelin and Sleep
Sleep, a quality that deteriorates with age, plays a very important role in the amount Human Growth Hormone our body produces. The majority of our natural HGH production is known to occur during deep sleep. Because the body produces HGH during deep sleep, less hours of sleep and poor sleeping patterns result in a low production of HGH.
Sermorelin Therapy promotes longer, deeper sleep and improved sleeping patterns. Production of HGH during the sleep cycle becomes dramatically improved. This deep restful sleep and increased production of HGH enhances the body’s ability to better recover and regenerate from daily life and exercise.
Sermorelin Therapy is proven to be effective for anti-aging purposes
One of the main benefits of Sermorelin therapy is that it is one of the best treatments to replace the body’s production of HGH that starts to decline at around the age of 30. Sermorelin Therapy is effective at restoring natural levels of the hormone, and there is no risk of overproduction of the hormone because the body regulates production of the hormone. It has shown to be an effective replacement for human growth hormone in aging adults, because it increases levels of the hormone gradually and uses the body’s natural pathways to deliver the hormone to tissues. The therapy has shown to be safe and effective at increasing HGH levels naturally, and thousands of people have tried it with excellent results under medical supervision.
Sermorelin Therapy vs. HGH Therapy
Sermorelin Therapy and HGH Therapy offer all of the same potential treatment benefits. Injections of Growth Hormone through HGH Therapy will have the same end result as the increased Growth Hormone produced by the body through Sermorelin Therapy. Although the end result of Sermorelin and HGH Therapy is the same, the avenue in which the result is accomplished is the biggest difference.
Sermorelin Therapy carries a significantly lower risk of overdose and possibility for abuse. The body will only use the amount of Sermorelin it needs to manufacture a healthy amount of Human Growth Hormone. Sermorelin will not encourage the body to produce excessive levels of HGH. For those who want faster results, HGH Therapy will be the preferred choice. HGH Therapy is quicker to take affect and permits for higher overall levels of HGH to be reached.
Sermorelin cost is typically less than HGH cost due to the intricate process involved to genetically engineer Human Growth Hormone. Both HGH and Sermorelin Therapy are a financial investment in your quality of life, health and well being. The rewards of either far outweigh any costs involved.
This treatment is prescribed for use in adults to increase lean muscle mass, reduce body fat, increase bone density, enhance the immune system, and strengthen the heart, as well as other organs of the body.
Since the increased volume of human growth hormone is produced by the body’s own pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by the Sermorelin GH-RH stimulation of the pituitary than the body can safely process.
In children, Sermorelin acetate (GHRH) has been approved for ramping up growth hormone levels that do not make enough and are deficient. It is on-label and FDA approved for this indication.
In adults, using it to increase growth hormone and IGF-1 levels is an off-label use of the drug. This means it can be prescribed by physicians who determine an indication to be appropriate, but it was not cleared by the FDA specifically for this purpose.
Sermorelin can be combined with hCG and Lipotropic MIC injections, Methyl B12 injections and other bio-identical hormones, as well as thyroid medications and adrenal boosting nutraceuticals (labs will be done for all of these to see your values and what you are deficient in).
Sermorelin does everything HGH therapy does without the side effects?
Studies have shown that Sermorelin helps decrease body fat, increase muscle mass, establish a natural sleep cycle, increase libido, increase energy levels, improve exercise recovery, and everything else that HGH therapy does without side effects and other negative effects. People who have tried human growth hormone on their own or under medical supervision have sometimes experienced several side effects which are thought by many to result from “flooding”the body with too much hormone. Some of the side effects that are thought to be associated with HGH therapy include carpal tunnel syndrome, kidney problems, higher cholesterol level, tingling in the skin, joint pain and nerve pain. These side effects have not been seen with Sermorelin Therapy, which makes it superior to HGH therapy in many cases.
What can I expect to experience on Sermorelin Therapy?
Increase in energy, sex drive, skin elasticity, muscle tone, stamina, focus, bone density, and mental functions. Patients can also expect to experience deeper, more restful sleep, fuller hair, and improved recovery time from wounds and illnesses. Also you should see a decrease in fat, wrinkles, cholesterol, cellulite, joint and muscle pain, fatigue and depression.
To completely appreciate the benefits of Sermorelin, first it is necessary to understand Human Growth Hormone (hGH). hGH is secreted by the pituitary gland and controls the growth of cells and organs in the body.
Natural hGH peaks at age 20. Beginning at age 30, humans experience a 14% reduction in hGH every decade of life. By age 40, the production of the human growth hormone is only 40% of what it was at 20. It is possible to stimulate the pituitary gland to produce hGH again, even after this decline in production has occurred, by using a Growth Hormone Releasing Factor (GRF).
GHRH for injection was approved in the treatment of growth hormone deficiency in children by the FDA in 1997. This therapy consists of daily injections of Sermorelin acetate which stimulates the pituitary gland to produce increased natural secretion of human growth hormone. Since Sermorelin acetate is approved as safe for use in children to increase their production of growth hormone, it is considered safe for use in increasing the natural production of growth hormone in adults deficient in growth hormone.
This treatment is prescribed for unlabeled use in adults to increase lean muscle mass, reduce body fat, increase bone density, enhance the immune system, and strengthen the heart, as well as, other organs of the body. Since the increased volume of human growth hormone is produced by the body’s pituitary gland, the body’s endocrine system will not allow more growth hormone to be produced by the Sermorelin GH-RH stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system.
Unlike hGH the Human Growth Hormone itself, Sermorelin affects a more primary source of failure in the GH neuroendocrine axis, has more physiological activity, has a better safety profile, and its use for adult hormone deficiency is not restricted.
How long does it take to work?
Just like most peptide hormones, Sermorelin usually has a “loading” period of 3-6 months before full effects are noticed. Once injected, both Sermorelin and rHGH are eliminated from then body very quickly and therefore need to be injected frequently. Its actions are dependent on a chain reaction of biological processes which result in elevated and sustained HGH and growth factors. It takes some time for levels to become optimal and initiate the benefits we are seeking to achieve.
How much Sermorelin acetate should I injection? What dosage should men and women use?
Sermorelin acetate dosage for men will depend upon a number of factors such as IGF-1 levels, weight, height and age. Usually the dosage for men using Sermorelin is 200 to 300mcg per evening.
Sermorelin acetate dosage for women will also depend on factors related to her IGF-1 score, body fat percentage, how tall she is and age in years. Usually women use a dosage of 100 to 200 mcg per evening.
Injectable Sermorelin Dosage for Muscle Growth and Body Building
It is not FDA approved and illegal to use sermorelin for the purposes of muscle development, growth, performance enhancement and body building. Body builders use dangerously high doses in the 500mcg to 1000mcg which push their IGF-1 levels over 300 ng/dl and will suffer side effects like a distended gut (swollen belly), carpal tunnel syndrome, and bloating. They also put themselves at risks for other diseases. We list a number of the diseases, risks and dangers of Sermorelin / HGH abuse and overdosing.